文献简介

出版社:Pediatr Allergy Immunol

作  者:Sanna Poikonen, Tuija J. Puumalainen, Hannu Kautiainen, Timo Palosuo, Timo Reunala1 and Kristiina Turjanmaa

编  号:10.1111/j.1399-3038.2007.00666.x

关键字:atopic dermatitis; food allergy; oilseed rape; turnip rape

年  份:2008   点击量:990

文献摘要

 Turnip rape and oilseed rape 2S albumins are new allergens in children with atopic dermatitis suspected for food allergy. We recently found that 11% (206/1887) of these children had a positive skin prick test to seeds of oilseed rape (Brassica napus) and/or turnip rape (Brassica rapa).

  白菜型油菜和油菜2S白蛋白被怀疑是特应性皮炎患儿食物过敏的新过敏原。最近我们发现11%(206/1887)的患儿在对油菜(欧洲油菜)和(或)白菜型油菜(芜菁)种子的皮肤点刺试验中呈现出阳性。

 

  In the present case-control study we examined how the children with atopic dermatitis sensitized to turnip rape and oilseed rape had been breast-fed and whether they had some common sensitization pattern to certain foods or pollens. A total of 64 children with atopic dermatitis and a positive skin prick test to turnip rape and/or oilseed rape (5 mm) were examined. Sixty-four age- and sex-matched children with atopic dermatitis but negative skin prick tests to turnip rape and oilseed rape served as case controls.

  在本病例对照研究中,我们调查了对白菜型油菜和油菜过敏的特应性皮炎患儿是如何一直用母乳喂养的,以及他们是否对某些食物或花粉有普遍的致敏模式。共对64名对球茎甘蓝和或)油菜(5 mm)的皮肤点刺试验呈阳性的特应性皮炎患儿进行了调查,病例对照为64名年龄和性别与其匹配的特应性皮炎患儿,但是对球茎甘蓝和油菜的皮肤点刺试验结果为阴性。

 

  The turnip rape and/or oilseed rape sensitized children with atopic dermatitis had significantly more often positive skin prick tests reactions and IgE antibodies to various foods (cow’s milk, egg, wheat, mustard; p < 0.01) and pollens (birch, timothy, mugwort; p < 0.01) than the control children.

与对照组患儿相比,对白菜型油菜和或)油菜过敏的特应性皮炎患儿的皮肤点刺试验反应明显更经常呈阳性,且对各种食物(牛奶、鸡蛋、小麦、芥末;p<0.01)和花粉(桦树、梯牧草、艾蒿;p <0.01)均有IgE(免疫球蛋白E抗体。

 

  They had been exclusively breast-fed for a longer period (median 4 months; p < 0.05) and had more often associated asthma (36%) and allergic rhinitis (44%). Children with atopic dermatitis sensitized to oilseed rape and turnip rape had high frequency of associated sensitizations to all foods and pollens tested showing that oilseed plant sensitization affects especially atopic children who have been sensitized to multiple allergens.

他们被专门用母乳喂养了一长段时间(平均为4个月,P <0.05),且更经常患哮喘(36%)和过敏性鼻炎(44%)。研究发现对油菜和白菜型油菜过敏的特应性皮炎患儿在所有食物和花粉的过敏测试中相应的致敏频率高,这表明油料作物使特异性患儿致敏,尤其是有多种过敏原过敏的患儿。



Poikonen S.et.al. Pediatr Allergy Immunol 2008: 19: 408–411