文献简介

出版社:JAMA

作  者:ErikaL.Hagstrom,MD;DylanHaynes,BS;AlexG.Ortega-Loayza,MD

编  号:

关键字:增殖型天疱疮

年  份:2020   点击量:228

文献摘要 全文翻译

A woman in her 80s presented with an 8-month history of a growing, painful tumor on her right buttock. The patient felt well otherwise and denied experiencing fevers, chills, sweats, weight loss, or malaise. Her medical history was not able for chronic kidney disease and genital herpes simplex virus (HSV). She reported no history of genital warts, HIV, or inflammatory bowel disease. A biopsy was performed, and results were consistent with a noninfectious, granulomatous ulcer. Based on the clinical appearance and prior pathologic findings, the patient received treatment of oral antibiotics, intralesional steroids, topical steroids, and immunomodulators, without improvement. Findings from colorectal surgical evaluation of the internal anal mucosa were negative for malignant neoplasm.

患者女性80余岁,因右臀部8个月逐渐发展的疼痛肿瘤而就诊。患者感觉良好,否认出现发烧、发冷、出汗、体重减轻或不适症状。患者无慢性肾脏疾病和生殖器单纯疱疹病毒(HSV)用药史。且患者自述无尖锐湿疣、HIV或炎性肠病病史。进行了活组织检查,结果符合非感染性肉芽肿性溃疡特征。根据临床表现和先前病理发现,患者接受了口服抗生素、皮内输注类固醇、外用类固醇和免疫调节剂治疗,但未改善。直肠内肛门粘膜手术评估结果恶性肿瘤阴性。