文献简介

出版社:JAMA

作  者:K. Maharaja, MD; Vishal Gupta, MD; Sujay Khandpur,MD

编  号:

关键字:溃疡;组织胞浆菌病

年  份:2015   点击量:64

文献摘要 全文翻译

A 40-year-old man, who resided in the eastern part of India, was referred to us from the department of otorhinolaryngology for evaluation of a nonhealing ulcer on the tongue present for the last 4 months. The lesion had started as a small painless mass on the right lateral aspect of the tongue, which gradually grew and subsequently ulcerated. It was asymptomatic except for causing mild difficulty in eating. He denied consuming tobacco or alcohol regularly. He had type 2 diabetes mellitus for 2 years, which was well controlled with oral hypoglycemic agents. The patient had no systemic complaints. There was no history of high risk behavior for human virus (HIV) acquisition. On physical examination, there was a single well-defined ulcer measuring 2 × 2 cm on the right lateral aspect of tongue with a clean base and irregular and elevated heaped-up margins (Figure 1A). There was no underlying induration, friability, or bleeding on manipulation. The rest of the oral cavity was normal. A 3-mm punch biopsy from the edge of the ulcer was taken and sent for histopathological examination (Figure 1B and C).

患者男性,40余岁,印度东部人,由耳鼻喉科转诊至皮肤科,以评估过去四个月舌部未愈合溃疡。皮损开始时为右侧舌部小块无痛性肿块,随后逐渐增大、溃烂。除了引起轻微进食困难外,无其他症状。患者否认经常吸烟或饮酒。患者患2型糖尿病2年,口服降糖药控制良好,且无全身症状。患者无HIV高危风险行为史。体格检查示,舌右侧面有一2 × 2 cm边界清楚的溃疡,基底干净、不规则,边缘隆起(图1A)。无潜在硬结、易脆或出血。口腔其余部位正常。从溃疡边缘取3mm钻孔活检标本并进行组织病理学检查(图1B和C)。