文献简介

出版社:JAMA

作  者:Paola C. Aldana, BS; Gibran Shaikh, MD; Marcia S. Driscoll, MD, PharmD

编  号:

关键字:异色病样;蕈样肉芽肿病

年  份:2019   点击量:159

文献摘要 全文翻译

A man in his 40s with a 5-year history of mildly pruritic poikilodermatous patches and thin plaques involving the bilateral axilla and groin presented with expanding lesions on both flanks. He had not received any prior treatment for the lesions. On examination, there were hypopigmented and hyperpigmented reticulated patches and thin, atrophic plaques covering more than 10% of the total body surface area involving the axilla, groin, and flanks bilaterally (Figure, A). No cervical, axillary, or inguinal lymphadenopathy was noted. Results from a comprehensive review of systems was unremarkable. Results from a complete blood cell count, erythrocyte sedimentation rate, and blood chemistry analyses were normal. A 6-mm punch biopsy specimen from the right flank was obtained for histopathological examination (Figure, B). Immunohistochemical analysis was also performed (Figure, C and D).

患者男性40余岁,有5年轻度瘙痒皮肤异色斑片和稀薄斑块病史,累及双侧腋窝和腹股沟,且双侧腹皮损扩展。患者先前未接受任何治疗。检查发现全身10%以上面积可见色素减退和色素沉着过度网状斑块和稀薄萎缩斑块,累及腋窝、腹股沟和侧腹(图A)。未发现颈部、腋窝或腹股沟淋巴结肿大。系统全面检查结果未见异常。全血细胞计数、红细胞沉降率和血液化学分析结果正常。取右腹侧钻孔活检标本用于组织病理学检查(图B)。行免疫组化分析(图C和D)。