文献简介

出版社:JAMA Dermatology

作  者:Jaime Matarredona, MD; Javier García-Abellán, MD; Isabel Valencia Ramírez, MD

编  号:

关键字:持久性豆状角化过度病;丘疹

年  份:2019   点击量:79

文献摘要 全文翻译

A man in his 60s presented with a 10-year history of a slowly progressive, asymptomatic cutaneous eruption on his left leg (Figure 1A). He had a 16-year history of diabetes mellitus that was being treated with metformin. Hematological and biochemical test results were unremarkable. There was no history of another endocrine disorder or malignant neoplasm. There was no family history of similar cutaneous findings. Physical examination revealed reddish brown hyperkeratotic papules 1 to 10mm wide on the front and back of the left leg from knee to ankle. The rest of the physical examination findings were unremarkable. Removal of the scales caused slight bleeding. A lesional skin biopsy was performed (Figure 1B and C).

患者男性,60余岁,左腿部有10年缓慢进展的无症状红斑病史(图1A)。患者有16年糖尿病史,正接受二甲双胍治疗。血液学和生化检查结果无显著异常。患者无其他内分泌紊乱或恶性肿瘤病史,且无类似皮肤病家族史。体格检查显示左腿膝盖到脚踝处可见1~10mm的红棕色角化过度丘疹。其余部位体格检查无异常。去除鳞屑导致轻微出血。对病变皮肤进行组织活检(图1B和C)。