文献简介

出版社:JAMA Dermatology

作  者:Nirali Patel, MS; Hayley Goldbach, MD; Marcia Hogeling, MD

编  号:

关键字:环状红斑

年  份:2018   点击量:84

文献摘要 全文翻译

A young child presented to clinic with a 6-month history of an asymptomatic expanding erythematous eruption on the lower legs, abdomen, and buttocks (Figure, A). The eruption would wax and wane, with each episode lasting for approximately 1 week, without residual pigmentation. Clinical examination was significant for faint, nonscaling annular serpiginous, erythematous plaques with central clearing, and barely elevated borders. Test results for erythrocyte sedimentation rate, complete blood cell count, antinuclear antibodies, anti-Ro/SSA and anti-La/SSB antibodies, and Borrelia burgdorferi antibodies were within normal limits. There was no family history of autoimmune disease, and the child had not experienced any fevers or exposures to ticks or other arthropods. A punch biopsy specimen from the left thigh was obtained, and histopathological analysis was subsequently performed (Figure, B and C).

患者年幼儿童,小腿、腹部和臀部有6个月无症状扩张红斑病史(图A)。皮疹大小有变化,每次暴发持续时间约1周,无残留色素沉着。临床检查可见不明显、无鳞屑环状匐行红斑,中心消退,边界未隆起。红细胞沉降率、全血细胞计数、抗核抗体、抗Ro / SSA和抗La / SSB抗体以及伯氏疏螺旋体抗体的测试结果均在正常范围内。患者无自身免疫性疾病家族史,且未发烧或接触过蜱或其他节肢动物。取左大腿钻孔活检标本,用于组织病理学分析(图B和C)。