文献简介

出版社:JAMA Dermatology

作  者:Athena J. Manatis-Lornell, BA; Maryanne M. Senna, MD

编  号:

关键字:Miliary osteoma cutis

年  份:2018   点击量:294

文献摘要 全文翻译

A woman in her 50s with biopsy-proven scalp lichen planopilaris (LPP) presented with an increasing number of slightly pruritic facial papules that coincided with the start of her hair loss condition (Figure, A). She denied a history of severe acne or other inflammatory skin disorders. The patient had no health problems and only had a distant medical history of an appendectomy and an oophorectomy. The only medication she was taking was hydroxychloroquine 200mg twice daily that was initiated as treatment of her LPP and did not improve the appearance or symptoms of her facial papules. On physical examination, she had numerous 1-mm skin-colored grouped monomorphic noninflammatory papules on the bilateral temples, the bilateral cheeks, and the chin. A 3-mm punch biopsy specimen was obtained for histopathologic examination of a representative lesion on the right chin (Figure, B and C).

患者女性,50余岁,伴有经活检证实的头皮毛发扁平苔藓(LPP),表现为面部出现越来越多的轻度瘙痒丘疹,与初期出现脱发症状一致(图A)。患者否认有严重痤疮或其他炎症性皮肤病史。患者无任何健康问题,仅有阑尾切除术和卵巢切除术远期病史。患者唯一用药史为开始治疗LPP时服用羟氯喹,每日两次,每次200 mg,且患者面部丘疹外观或症状并未改善。体检发现,患者双侧太阳穴、双侧脸颊、下颏处有大量1mm肤色单形非炎性丘疹。右颏典型皮损处取3mm钻孔活检标本用于组织病理学检查(图B和C)。