文献简介

出版社:JAMADermatology Clinicopathological Challenge

作  者:Jason E. Hawkes, MD; Scott R. Florell, MD; David A.Wada, MD

编  号:

关键字:皮肤毛霉菌病

年  份:2015   点击量:24

文献摘要 全文翻译

A man in his 50s was referred to the dermatology clinic for a chronic, painful nonhealing ulcer on the right forearm following a ground-level fall 3 months previously. He reported subjective fevers, as well as increasing erythema and tenderness immediately around the right forearm lesion. He stated that he did not have a history of poor wound healing or painful skin ulcers. He had a history of type 2 diabetes and an allogenic bone marrow transplant 1 year prior for myelodysplastic syndrome complicated by pancytopenia and chronic graft-vs-host disease. Physical examination revealed an isolated slightly erythematous, edematous plaque with a prominent central eschar on the right forearm (Figure, A). An incisional biopsy at the edge of the eschar was performed, and a specimen was sent for pathological evaluation (Figure, B-D).

患者男性,50余岁,3个月前因摔倒后,右前臂上出现慢性非愈合疼痛溃疡至皮肤科就诊。患者自述自觉发热,同时右前臂皮损周围红斑增加,有压痛感,且患者无伤口愈合困难史或皮肤溃疡病史。患者曾有2型糖尿病史,且1年前因骨髓增生异常综合征合并全血细胞减少症和慢性移植物抗宿主病接受同种异体骨髓移植。体格检查示右前臂可见一孤立红色水肿斑块,中心结痂(图A)。痂皮边缘行切开活检,标本送组织病理学检查和评估(图B-D)。