文献简介

出版社:JAMA Dermatology

作  者:Courtney Gwinn, MD; Jason E. Hawkes, MD; Keith L. Duffy, MD

编  号:

关键字:Cutaneous Bacillus cereus infection

年  份:2017   点击量:116

文献摘要 全文翻译

A female infant with relapsed refractory infantile acute lymphoblastic leukemia, blast crisis (>60% blasts), and central nervous system involvement was admitted for reinduction chemotherapy with cytarabine, vincristine, daunorubicin, methotrexate, and dexamethasone. Seventeen days after her last day of chemotherapy, while neutropenic, she became febrile and developed several vesicles with an erythematous base on the lower back (Figure, A) and left thigh. Tissue and blood cultures and a punch biopsy specimen of a vesicle on the lower back were obtained. Hematoxylin-eosin (Figures, B and C), gram(Figure, D), and periodic acid-Schiff stains were performed on the punch biopsy. Testing for herpes simplex virus and varicella zoster virus were also ordered.

一女婴,复发性难治性小儿急性淋巴细胞性白血病急性期,且中枢神经系统受累,再次接受诱导化疗伴阿糖胞苷、长春新碱、柔红霉素、甲氨蝶呤和地塞米松治疗。化疗后17天,患者出现中性粒细胞减少、发热,且下背部和左大腿可见若干水疱伴红斑(图A)。取下背部水疱进行组织和血液培养和钻孔活检。对钻孔活检标本进行HE染色(图B和C)、革兰氏染色(图 D)和过碘酸雪夫染色。且对单纯疱疹病毒和水痘带状疱疹病毒进行了检测。