文献简介

出版社:国际皮肤性病学杂志

作  者:余韦臻,徐慧,袁华英

编  号:

关键字:皮肤;细胞衰老;大气;颗粒物;空气污染物;PM2.5

年  份:2017   点击量:66

文献摘要

【Abstract】Atmospheric particulate matter is one of the major air pollutants,and also the chief pollutant affecting air quality in cities.At present,the impacts of atmospheric particulate matter on health have drawn great public attention.Among all kinds of atmospheric particulate matter,the fine particulate matter with aerodynamic diameter≤2.5μm(PM2.5)has large specific surface area,and is easier to carry toxic substances,therefore,it dose greater harm to human body.Epidemiological studies and researches on related mechanisms have shown that air pollution can damage the skin by affecting its integrity, increase the production of free radicals through oxidative stress and inflammatory reactions,and finally accelerate extrinsic skin aging.Therefore, strengthening skin’s  defense against PM2.5 and applying antioxidants and aromatic hydrocarbon receptor antagonists can postpone skin aging to a certain extent.

【摘要】大气颗粒物是重要的空气污染物之一,也是影响城市空气质量的首要污染物,对健康的影响目前已成为关注的重点,其中大气颗粒物中空气动力学直径≤25μm的细颗粒物(PM2.5)比表面积大,易携带有毒物质,对人体的致病性更大。流行病学调查和相关机制的研究显示,空气污染也会影响皮肤的完整性,对皮肤造成危害,通过氧化应激和炎症反应使机体自由基产生增加,进而加速外源性皮肤老化。因此,加强皮肤对PM2.5的防御能力、应用抗氧化剂、芳香烃受体拮抗剂等能在一定程度上减缓皮肤衰老。