文献简介

出版社:

作  者:Nidhi Patel, Nilofar Diwan, Pragya A. Nair

编  号:

关键字:Acrokeratosis, church spires, Darier’s disease

年  份:2015   点击量:722

提  供:Indian Dermatology Online Journal - March-April 2015 - Volume 6 - Issue 2

文献摘要 全文翻译

ABSTRACT

Acrokeratosis verruciformis (AKV) of Hopf is an autosomal dominant genodermatosis with unknown etiology. It is characterized by multiple flat‑topped keratotic papules resembling planar warts located mainly on the dorsum of hands and feet.Superficial ablation is the treatment of choice. A 41‑year‑old female presented with multiple hyperpigmented, hyperkeratotic papules and plaques over flexor aspect of both forearms, extensors of both legs and dorsum of the feet. Histopathology showed changes of AKV. Patient was treated with a combination of topical corticosteroids and cryotherapy with no visible improvement.

摘要

Hopf疣状肢端角化病(AKV)是一种病因不明的,常染色体显性遗传性皮肤病。以多个类似于跖疣的扁平状角化性丘疹为特征,好发于手足背部。浅表磨削术是首选的治疗方法。患者女性,41岁,在其双前臂屈肌处,双下肢伸肌以及足背部可见多个色素沉着的、角化过度丘疹和斑块。组织病理显示AKV。应用局部皮质类固醇联合冷冻治疗进行治疗,但无明显改善。