文献简介

出版社:Anais Brasileiros de Dermatologia

作  者:Ana Carolina Handel,Luciane Donida Bartoli Miot,Hélio Amante Miot

编  号:10.1590/abd1806-4841.20143063

关键字:Contraceptives; Oral contraceptives; Pregnancy; Hormones; Gonadal steroid hormones; Melanosis;Pigmentation; Skin pigmentation; Ultraviolet rays; Pigmentation disorders

年  份:2014   点击量:1567

文献摘要 全文翻译

Abstract
Melasma is a chronic acquired hypermelanosis of the skin, characterized by irregular brown macules symmetrically distributed on sun-exposed areas of the body, particularly on the face. It is a common cause of demand for dermatological care that affects mainly women (especially during the menacme), and more pigmented phenotypes (Fitzpatrick skin types III-V). Due to its frequent facial involvement, the disease has an impact on the quality of life of patients. Its pathogeny is not yet completely understood, although there are some known triggering factors such as sun exposure, pregnancy, sexual hormones, inflammatory processes of the skin, use of cosmetics, steroids, and photosensitizing drugs. There is also a clear genetic predisposition, since over 40% of patients reported having relatives affected with the disease. In this manuscript, the authors discuss the main clinical and epidemiological aspects of melasma.

摘要

黄褐斑是一种慢性获得性色素沉着性皮肤病,以身体日光暴露部位(尤其是面部)对称分布不规则的褐色斑疹为特征。它是女性(尤其是经潮期中的女性)皮肤护理的常见需求,以及深肤色表型(Fitzpatrick皮肤类型III-V)。由于该病常累及面部,因而影响患者生活质量。尽管已明确一些诱发因素(如日光暴露、妊娠、性激素类药、皮肤的炎症过程,化妆品、类固醇和光敏药物的使用),但尚不完全了解其病因。由于报道超过40%的患者有亲属受累,因而其遗传易感性明显。本文作者讨论了黄褐斑的主要临床症状和流行病学知识。