文献简介

出版社:Medical Mycology February

作  者:YUMI AOYAMA*, MASAYO NOMURA, SHINYA YAMANAKA, YOKO OGAWA & YASUO KITAJIMA

编  号:

关键字:phaeohyphomycosis, Exophiala xenobiotica, Exophiala jeanselmei

年  份:2009   点击量:948

文献摘要

Phaeohyphomycosis is a rare fungal infection that is more commonly associated with immunocompromised patients. We present a case in which a 77-year-old woman with non-Hodgkin lymphoma developed subcutaneous phaeohyphomycosis caused by Exophiala xenobiotica. E. xenobiotica is a dematiaceous hyphomycete that was recently identified as a segregant of the E. jeanselmei complex. The patient was successfully treated with local excision of the lesions and post-surgical oral itraconazole. The latter was administered with the aim of preventing systemic dissemination in this immunocompromised patient.

暗色丝孢霉病是一种罕见的真菌感染性疾病,在免疫功能低下的患者中较为常见。我们报导一例77岁(女性)伴有非霍奇金淋巴瘤ExophialaXenobiotica引发的皮下暗色丝孢霉病的患者E. xenobiotica是一种暗色丝孢菌,近来被认为是 甄氏外瓶霉复合体的一种分离体。通过局部切除病变皮损以及术后口服伊曲康唑,患者被成功治愈。应用后者(口服伊曲康唑)的目的是为了防止在免疫功能低下的患者中出现全身性的播散。