文献简介

出版社:

作  者:Jonathan D. Foster, Faye A. Hartmann† and Karen A. Moriello*

编  号:10.1111/j.1365-3164.2012.01115.x

关键字:Erysipelothrix infection

年  份:2012   点击量:476

文献摘要

  Background Erysipelothrix rhusiopathiae is a Grampositive facultative anaerobe found worldwide and is most associated with skin disease in swine, while anecdotal reports of cases in dogs have been associated with endocarditis.

       Hypothesis ⁄ Objective- Clinicians should consider systemic infectious diseases as a potential cause of erythematous skin lesions.

  Animals – A 5-year-old female spayed Labrador retriever presented with lethargy, anorexia and erythematous skin lesions while receiving immunosuppressive therapy for immune-mediated haemolytic anaemia. Four days prior to presentation, the dog had chewed on a raw turkey carcase.

  Methods – Complete blood count, serum chemistry profile, urinalysis and blood cultures.

  Conclusions and clinical importance – This report is the first documentation, to the best of the authors’ knowledge, of Erysipelothrix infection, a known zoonosis, in an immunosuppressed dog, highlighting the need for infectious disease monitoring in patients receiving such therapy. This information may also help educate veterinarians to include Erysipelothrix infection as a differential diagnosis in dogs with fever and skin lesions, as well as the role of blood cultures in diagnosing this disease.

  背景

      猪丹毒杆菌是一种世界范围内的革兰氏阳性兼性厌氧菌,通常与猪身上的皮肤病相关联,但也有在狗类中与感染性心内膜炎相关的病例传闻被报道。

  假设⁄目标——临床医生应考虑把全身感染性疾病作为红斑性皮肤病变的潜在原因。

  试验动物——一只5岁的雌性已绝育的拉布拉多犬,病犬由于免疫介导的溶血性贫血而接受免疫抑制剂治疗后出现嗜睡、厌食症和红斑性皮肤病变。描述称在四天之前,这只狗啃过生火鸡骨头。

  方法——全血细胞计数,血清生化分析,尿液和血液培养。

  结果——血液培养得到一个清晰生长的血清型1b型红斑丹毒丝菌。连续两周每天两次口服22mg⁄ kg的阿莫西林并停止使用硫唑嘌呤能够缓解发烧和皮肤病变。