文章简介

出版社:Photodermatol Photoimmunol Photomed

作   者:El-Mofty M, Mostafa W, Youssef R, El-Fangary M, El-Ramly A, Mahgoub D, Fawzy M, El-Hawary M.

编   号:10.1111/phpp.12061.

年   份:2013    点击量:459

文章摘要

BACKGROUND:


Vitiligo is an acquired pigmentary disorder that affects between 1% and 2% of the general population. Phototherapy remains the cornerstone of treatment, with NB-UVB being the most frequently used. BB-UVA can be a plausible alternative for darker population; skin photo type III and IV.

PATIENTS AND METHODS:



The study was a prospective, randomizedcontrolled, and single-blinded clinical trial, conducted on 40 patients with bilateral symmetrical vitiligo. The patients were randomly divided into two equal groups; group (A) received a fixed dose of 15 J/cm(2) BB-UVA, while group (B) received NB-UVB. The study was conducted for a period of 16 weeks (48 sessions).

RESULTS:



The final percentage of clinical improvement was significantly higher (P = 0.047) within the BB-UVA group (63.82% ± 27.42), than within the NB-UVB group (44.32% ± 29.78).

CONCLUSION:


 
BB-UVA can be considered as an alternative treatment line for vitiligo.